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dopamine antagonist
A dopamine antagonist (antidopaminergic) is a type of drug which blocks dopamine receptors by receptor antagonism. Most antipsychotics are dopamine antagonists, and as such they have found use in treating schizophrenia, bipolar disorder, and stimulant psychosis. Several other dopamine antagonists are antiemetics used in the treatment of nausea and vomiting.
==Uses and examples==
Dopamine receptor antagonists are used for some diseases such as schizophrenia, bipolar disorder, nausea and vomiting. It can also control the symptoms of hypersexuality and increased orgasmic activity.
Antidopaminergics such as haloperidol can be an antidote for poisoning with cocaine, amphetamines and dopamine agonists such as bromocriptine and/or ropinirole.
* Agents such as atypical antipsychotics (coupled with serotonin antagonist effects): paliperidone, clozapine, risperidone, olanzapine, quetiapine, and ziprasidone
* Used as antiemetics: metoclopramide, droperidol, domperidone
* Used as tricyclic antidepressants: amoxapine, clomipramine, trimipramine
* Choline can antagonize dopamine directly or interfere with receptor function
* Melatonin suppresses dopamine activity as part of normal circadian rhythm functions, although pathological imbalances have been implicated in Parkinson's disease
抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』
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